Goodman and Gilman’s : The Pharmacological Basis of Therapeutics

Title of the book : The Pharmacological Basis of Therapeutics

Author                :  L.Brunton ,R.Hilal-Dandan,B. Knollmann

Edition                : 13th

Year                     : 2017

Book language  : English

File format          : PDF 

File  size               : 57.36 MB

pages                    : 1423

➤Description :

Goodman & Gilman's : The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman's careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease. The Thirteenth Edition includes more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action. With the addition of 30 new contributors, this updated edition continues to focus on the basic principles of pharmacology.

➤Contents : 

↦ Section I : General Principles

⧫ Chapter  1 : Drug Invention and the Pharmaceutical Industryharmacokinetics
⧫ Chapter  2 : Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination

⧫ Chapter  3 : Pharmacodynamics: Molecular Mechanisms of Drug Action

⧫ Chapter  4 : Drug Toxicity and Poisoning

⧫ Chapter  5 : Membrane Transporters and Drug Response

⧫ Chapter  6 : Drug Metabolism

⧫ Chapter  7 : Pharmacogenetics
↦ Section II : Neuropharmacology

⧫ Chapter  8 : Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

⧫ Chapter  9 : Muscarinic Receptor Agonists and Antagonists

⧫ Chapter 10 : Anticholinesterase Agents

⧫ Chapter 11 : Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

⧫ Chapter 12 : Adrenergic Agonists and Antagonists

⧫ Chapter 13 : 5-Hydroxytryptamine (Serotonin) and Dopamine

⧫ Chapter 14 : Neurotransmission in the Central Nervous System

⧫ Chapter 15 : Drug Therapy of Depression and Anxiety Disorders

⧫ Chapter 16 : Pharmacotherapy of Psychosis and Mania

⧫ Chapter 17 : Pharmacotherapy of the Epilepsies

⧫ Chapter 18 : Treatment of Central Nervous System Degenerative Disorders

⧫ Chapter 19 : Hypnotics and Sedatives

⧫ Chapter 20 : Opioids, Analgesia, and Pain Management

⧫ Chapter 21 : General Anesthetics and Therapeutic Gases

⧫ Chapter 22 : Local Anesthetics

⧫ Chapter 23 : Ethanol

⧫ Chapter 24 : Drug Use Disorders and Addiction
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↦ Section III : Modulation of Pulmonary, Renal, and Cardiovascular Function

⧫ Chapter 25 : Drugs Affecting Renal Excretory Function

⧫ Chapter 26 : Renin and Angiotensin

⧫ Chapter 27 : Treatment of Ischemic Heart Disease

⧫ Chapter 28 : Treatment of Hypertension

⧫ Chapter 29 : Therapy of Heart Failure

⧫ Chapter 30 : Antiarrhythmic Drugs

⧫ Chapter 31 : Treatment of Pulmonary Arterial Hypertension

⧫ Chapter 32 : Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs

⧫ Chapter 33 : Drug Therapy for Dyslipidemias

↦ Section IV : Inflammation, Immunomodulation, and Hematopoiesis

⧫ Chapter 34 : Introduction to Immunity and Inflammation

⧫ Chapter 35 : Immunosuppressants and Tolerogens

⧫ Chapter 36 : Immune Globulins and Vaccines

⧫ Chapter 37 : Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor

⧫ Chapter 38 : Pharmacotherapy of Inflammation, Fever, Pain, and Gout

⧫ Chapter 39 : Histamine, Bradykinin, and Their Antagonists

⧫ Chapter 40 : Pulmonary Pharmacology

⧫ Chapter 41 : Hematopoietic Agents: Growth Factors, Minerals, and Vitamins.

↦ Section V : Hormones and Hormone Antagonists

⧫ Chapter 42 : Introduction to Endocrinology: The Hypothalamic-Pituitary Axis

⧫ Chapter 43 : Thyroid and Antithyroid Drugs

⧫ Chapter 44 : Estrogens, Progestins, and the Female Reproductive Tractnthelmintic Drugs

⧫ Chapter 45 : Androgens and the Male Reproductive Tract

⧫ Chapter 46 : Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex.

⧫ Chapter 47 : Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia
⧫ Chapter 48 : Agents Affecting Mineral Ion Homeostasis and Bone Turnover

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↦ Section VI : Gastrointestinal Pharmacology

⧫ Chapter 49 : Pharmacotherapy for Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease.
⧫ Chapter 50 : Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease
⧫ Chapter 51 : Pharmacotherapy of Inflammatory Bowel Disease

↦ Section VII : Chemotherapy of Infectious Diseases

⧫ Chapter 52 : General Principles of Antimicrobial Therapy
⧫ Chapter 53 : Chemotherapy of Malaria
⧫ Chapter 54 : Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections.
⧫ Chapter 55 : Chemotherapy of Helminth Infections
⧫ Chapter 56 : Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections.
⧫ Chapter 57 : Penicillins, Cephalosporins, and Other β-Lactam Antibiotics
⧫ Chapter 58 : Aminoglycosides
⧫ Chapter 59 : Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents
⧫ Chapter 60 : Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy
⧫ Chapter 61 : Antifungal Agents

⧫ Chapter 62 : Antiviral Agents (Nonretroviral)
⧫ Chapter 63 : Treatment of Viral Hepatitis (HBV/HCV)
⧫ Chapter 64 : Antiretroviral Agents and Treatment of HIV Infection

↦ Section VIII : Pharmacotherapy of Neoplastic Disease

⧫ Chapter 65 : General Principles in the Pharmacotherapy of Cancer
⧫ Chapter 66 : Cytotoxic Drugs
⧫ Chapter 67 : Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules
⧫ Chapter 68 : Hormones and Related Agents in the Therapy of Cancer

↦ Section IX : Special Systems Pharmacology

⧫ Chapter 69 : Ocular Pharmacology
⧫ Chapter 70 : Dermatological Pharmacology
⧫ Chapter 71 : Environmental Toxicology: Carcinogens and Heavy Metals

⧫ Appendices

⧫ Index